The most prominent systemic manifestations of inflammation include the following:
- The acute-phase reaction, modifications in WBC count and fever.
- The liver rises the synthesis of acute-phase proteins such as Fibrinogen, C-reactive protein (CRP) and serum amyloid A protein (SAA) that all serve unalike defense functions.
- Increase in WBC count. Normal is 4-10.
- Sepsis can take place.
